C&P Endocrine Disorders

Six months after the initial diagnosis

Hypothyroidism without myxedema

Hypothyroidism manifesting as myxedema (cold intolerance, muscular weakness, cardiovascular involvement (including, but not limited to hypotension, bradycardia, and pericardial effusion), and mental disturbance (including but not limited to dementia, slowing of thought, and depression))

Asymptomatic

Symptoms such as fatigue, anorexia, nausea, or constipation that occur despite surgery; or individuals that are not candidates for surgery, but require continuous medication for control.

Hypercalcemia (indicated by at least one of the following: Total Ca greater than 12 mg/dL (3-3.5 mmol/L), Ionized Ca greater than 5.6 mg/dL (2-2.5 mmol/L), creatinine clearance less than 60 mL/min, bone mineral density T-score less than 2.5 SD (below mean) at any site or previous fragility fracture)

For six months from the date of discharge following surgery

For three months after initial diagnosis

With striae, obesity, moon face, glucose intolerance, and vascular fragility.

Proximal upper or lower extremity muscle wasting that results in inability to rise from squatting position, climb stairs, rise from a deep chair without assistance, or raise arms.

As active, progressive disease, including areas of osteoporosis, hypertension, and proximal upper and lower extremity muscle wasting that results in inability to rise from a squatting position, climb stairs, rise from a deep chair without assistance, or raise arms.

Enlargement of acral parts or overgrowth of long bones

Arthropathy, glucose intolerance, and hypertension.

Evidence of increased intracranial pressure (such as visual field defect), arthropathy, glucose intolerance, and either hypertension or cardiomegaly

With persistent polyuria or requiring continuous hormonal therapy.

For three months after initial diagnosis

Corticosteroid therapy required for control

Weakness with fatigability

Two to four episodes during the past year

One or two crises during the past year

Three crises during the past year or five or more episodes during the past year.

Four or more crises during the past year